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Lady's Mantle Extract (Alchemilla Vulgaris Extract): Ellagitannins as Astringent Lead Marker in Three Carrier Variants
Lady's mantle (Alchemilla vulgaris) provides, with the CONIUNCTA® Alchemilla Vulgaris Extract, an ellagitannin-rich, aqueous-glycerolic or aqueous-glycolic extract with the INCI designation Alchemilla Vulgaris Extract. The extract is available in three carrier variants: Pentylene Glycol, Propylene Glycol and Glycerin. For formulators, it combines a clearly documented polyphenol profile with an astringent and balancing application focus, thereby covering both skin care and, in the glycerin variant, functional food applications. Ellagitannins as the analytical lead marker The characteristic marker of the lady's mantle extract is the ellagitannins, calculated in total as ellagic acid. The content in the dried plant, according to the literature (Hagers Handbuch, Wichtl 2009), lies between 2 and 8 percent; the product itself indicates an indicative range of 0.5 to 2.5 mg/mL. The underlying data is of review-level character. As a further documented compound, the extract contains quercetin glycosides in a range of 0.5 to 1 percent. The native extract has a DER of 1:10, and the extract fraction of the final product is around 30 percent. At an extract usage of 2 percent, this equates to a calculated 10.0 to 50.0 µg/mL ellagitannins introduced into the formulation. This figure allows a comprehensible calculation of the marker input via the chosen usage concentration. Documented efficacy profile: astringent, balancing, pro-age The effects documented in the CDS for ellagic acid include astringent, antioxidant and pore-refining properties. The regulatory-supported claim areas for cosmetics on record are astringent, balancing, elasticity support, glow/radiance, hormone-balancing as well as pro-age. As molecular targets, the data sheet lists protein precipitation (the basis of the astringent effect) and MMP-1 inhibition. For formulators, this means a clearly defined field of application: astringent and pore-refining care concepts, balancing formulations for a more even skin texture, as well as pro-age approaches relating to elasticity. The claims are closely tied to the data sheet; further-reaching medical or disease-related statements are not part of the documentation. Comparison of three carrier variants The extract is available in three standardization media, which differ in composition and application context: Glycerin (INCI: Glycerin, Alchemilla Vulgaris Extract): glycerolic preparation with approx. 30 percent extract content and approx. 70 percent glycerin (anhydrous, ≥ 99.5%). According to the data sheet, this variant is suitable for food applications. Propylene Glycol (INCI: Aqua, Propylene Glycol, Alchemilla Vulgaris Extract): composition approx. 40 percent water, 30 percent extract and 30 percent propylene glycol. Pentylene Glycol (INCI: Aqua, Pentylene Glycol, Alchemilla Vulgaris Extract): composition approx. 50 percent water, 30 percent extract and 20 percent pentylene glycol. All variants are suitable for cosmetic applications (EC No. 1223/2009). The selection depends on the carrier system of the target formulation and the desired functional additional benefit of the diol. Our technical team is available to clarify specific formulation and selection questions individually. Usage concentration and formulation framework For cosmetic applications, a general usage concentration of 2 to 5 percent is documented; for a specific cosmetic claim, 1 to 3 percent is indicated. For functional foods and beverages, the data sheet states a range of 0.5 to 2 percent, whereby an application of 1.3 percent calculates to 6.3 to 31.3 µg/mL ellagitannins. The extract is a raw material for further processing; the final suitability assessment for the respective application lies with the processing company. The product's color ranges from amber to light brown, with a density between 1.03 and 1.06. It is a clear liquid with a characteristic color. Note that color changes as well as possible turbidity or precipitation may occur depending on storage and temperature; filtration is possible in such cases and does not impair product quality. Regulatory status, purity and food suitability The extract is free of fragrance allergens subject to labeling requirements under Annex III of Regulation (EC) No. 1223/2009 and is suitable for vegan formulations. According to the safety data sheet, it is not a hazardous substance under Regulation (EC) No. 1272/2008: no pictogram, no signal word, no H- or P-statements required. It is not a PBT or vPvB substance, and no endocrine-disrupting properties are indicated under the relevant REACH provisions. The glycerin carrier variant is suitable for food applications and addresses the areas nutritional antioxidant and traditional dietary ingredient listed in the data sheet. Shelf life is 24 months under dry storage in the original sealed container between 10 and 30 °C. CONIUNCTA® extracts are manufactured in Germany using the proprietary AVE technology (Adaptive Vacuum Extraction). All batch-specific parameters (pH, relative density, refractive index) can be found in the respective CoA and are available via our technical documentation. Positioning within the portfolio and sourcing The lady's mantle extract joins our range of classic plant extracts and complements, in particular, astringent and pro-age-oriented formulation concepts. For aqueous and glycerolic systems, the glycerin variant is available, which is additionally documented for food applications; the diol variants Pentylene Glycol and Propylene Glycol offer options for different cosmetic carrier systems. Formulators, buyers and product developers can find all three variants in the shop: view Lady's Mantle Extract in the CONIUNCTA® shop. Our technical team is happy to advise individually on carrier selection and integration into existing formulations. CONIUNCTA® – raw materials, data and services for future-proof formulations.
Chamomile Powder Extract 10:1 (Chamomilla Recutita): Apigenin-7-glucoside in the Spray-Dried Flower Extract
The Chamomile Powder Extract 10:1 from CONIUNCTA® (INCI: Chamomilla Recutita) is a spray-dried flower extract powder that transfers the characteristic phytochemistry of the chamomile flower into a dry, dosable form. As a 10:1 concentrate with maltodextrin as carrier, this raw material is aimed at formulators in the cosmetics and food industries seeking an anhydrous, easy-to-handle chamomile base for powder applications, capsules, sticks, or reconstitutable systems. This article examines origin, marker compound, carrier system, and documented application profile based on TDS and CDS. Powder Form Instead of a Carrier Liquid: What Sets the 10:1 Concentrate Apart Unlike liquid chamomile extracts based on glycerin or oil, this raw material is available as a brown powder. According to the TDS, ethanol and water serve as extraction solvents; after extraction, the concentrate is spray-dried with maltodextrin as carrier. The documented composition is 80 to 99% chamomile extract and 1 to 20% maltodextrin. The extract ratio of 10:1 describes the concentration relative to the starting flower material. The particle fineness is specified in the TDS as 80 mesh (at least 95% passing through 80 mesh), with a bulk density of 0.50 to 0.70 according to product data. These parameters are relevant for formulators when it comes to dry blends, flow behavior, and weighing. The color ranges from golden yellow to light brown; a note in the dossier indicates that color changes may occur depending on storage and temperature, which is typical for a natural plant extract powder. Apigenin-7-glucoside as the Primary Marker The primary marker of chamomile listed in the CDS is apigenin-7-glucoside, a flavone glycoside. The content in the dried plant material is stated as 0.3 to 1%, with an indicative content in the product of 21 to 90 mg/g. The Ph. Eur. (minimum requirement of 0.25% apigenin-7-glucoside) and ESCOP serve as references. This marker is suitable as an analytical reference point for batch evaluation. Beyond the flavone, the CDS documents further characteristic compounds of the chamomile flower: (-)-alpha-bisabolol, which occurs at 0.1 to 0.5% of the flower in the essential oil, as well as chamazulene, which is formed from matricin and is likewise attributable to the essential oil. These figures describe the phytochemical profile of the raw material. Batch-specific analytical data are available upon request and by prior arrangement, according to the CDS. Documented Application Profile in Cosmetics For cosmetic application, the CDS lists the properties soothing and anti-inflammatory, each based on the phytochemical profile and published literature. The dossier explicitly notes that these claims require independent substantiation in accordance with Regulation (EC) No. 655/2013. Formulators should therefore substantiate efficacy claims in the finished product accordingly. In the
Corn Silk Powder Extract 10:1 (Zea Mays Silk): Maysin as Flavone C-Glycoside in the Spray-Dried Powder
Corn silk, botanically referred to as Zea Mays Silk, consists of the fine, golden-yellow fiber bundles (stigmas) of the corn plant. CONIUNCTA® offers this raw material as Corn Silk Powder Extract 10:1 (INCI: Zea Mays Silk): a spray-dried powder obtained through a concentration factor of 10:1 and stabilized on a maltodextrin carrier. For formulators in the cosmetics and food industries, the powder form is of interest because it can be incorporated into both aqueous and dry systems and is supplied without any carried-over solvent. Maysin: The Documented Lead Marker At the center of the analytical profile is maysin, a flavone C-glycoside listed in the datasheet as the primary marker of this extract. The literature content in the dry material is stated as 0.1 to 0.5% (source: Ren et al. 2013). Applying the concentration factor of 10:1 and an assumed recovery of 70 to 90%, this results in an indicative content in the product of 7 to 45 mg/g. At an extract usage level of 2%, this corresponds mathematically to approximately 0.14 to 0.90 mg/g in the finished formulation. These figures are based on review-level literature data and are to be understood as indicative, not as a guaranteed batch value. For maysin, the datasheet documents a biochemical profile described as antioxidant, anti-inflammatory, and capillary-strengthening; ROS scavenging, MMP inhibition, and NF-κB are named as molecular targets. This information originates from published literature and the biochemical profile and should accordingly be classified as literature-based. Further Documented Compounds In addition to maysin, the datasheet lists two further constituents: allantoin at a content of 0.1 to 0.3%, and potassium as a mineral component. Both round out the compound profile of the corn silk extract and are part of the plant's natural spectrum of constituents. Beyond the information stated in the CDS, CONIUNCTA® makes no further claims regarding concentrations or standardizations. Cosmetic Activity Profile and Regulatory Framework Based on the biochemical profile and published literature, the datasheet supports, for this extract, the cosmetic claim of an anti-inflammatory orientation in the cosmetic sense. Important for finished product manufacturers: such claims require independent substantiation by the party placing the product on the market, in accordance with Regulation (EC) No. 655/2013. Responsibility for the substantiation of the advertising claim on the end product therefore lies with the manufacturer of the finished formulation. CONIUNCTA® supplies the raw material together with the documented basis; product-specific proof of efficacy within the concrete cosmetic system remains the task of the user. Traditionally, a diuretic use has been attributed to the plant. This is expressly a traditional use and not a substantiated cosmetic or regulatorily supported claim; it is mentioned here only for botanical context. Powder Form, Carrier, and Technical Parameters The extract is available as a brown powder; the product color is described as golden yellow to light brown. It is obtained using ethanol and water as extraction solvents and subsequently spray-dried. The composition comprises 80 to 99% Corn Silk Extract and 1 to 20% maltodextrin as the carrier system. The particle size is specified as 80 mesh (at least 95% passing through 80 mesh), and the bulk density is 0.50 to 0.70. Odor, color, and taste are organoleptically described as characteristic. Extract ratio: 10:1, spray-dried Carrier: maltodextrin Recommended usage concentration in cosmetics: 2 to 5% (the




