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Dragon Blood Tree Extract (Harungana Madagascariensis Extract): Quercetin Glycosides for Antioxidant and Balancing Formulations

The dragon blood tree (Harungana madagascariensis) provides, through the CONIUNCTA® Dragon Blood Tree Extract (INCI: Harungana Madagascariensis Extract), a botanical raw material whose efficacy profile is closely aligned with its lead marker, the quercetin glycosides. The extract is available in three carrier variants: Pentylene Glycol, Propylene Glycol and Glycerin, each as a clear liquid with an amber to light brown tint. For formulators in cosmetics and novel food, this results in a versatile water-based raw material with a documented antioxidant focus. Quercetin Glycosides as Analytical Lead Marker The characterisation centres on the quercetin glycosides, a group of flavonoid glycosides. In the product they are specified at an indicative 74 to 315 µg/mL; in dried plant material the literature content according to the CDS is 0.3 to 1 percent (source: Moulari 2006, Planta Med). The extract is defined with a drug-to-extract ratio of 1:10 and an extraction efficiency of 70 to 90 percent. Harunganin is cited as an additional functional active; no separate concentration data are available for this compound. Documented Efficacy Profile for Skin Care The CDS describes for the extract an antioxidant activity (ROS scavenging), an anti-inflammatory activity via COX-2 inhibition, and a skin-brightening effect via tyrosinase inhibition. On this basis, the claim areas anti-ageing, balancing, pore-refining and skin-plumping are documented within the meaning of Regulation (EU) No 655/2013. These statements are to be understood as cosmetically compliant and relate to the appearance of the skin, not to medical effects. The targets cited in the data sheet, namely ROS scavenging, tyrosinase and COX-2, position the extract thematically in formulations addressing a balanced, plump-looking complexion. At a use concentration of 2 percent, the extract delivers a calculated 1.5 to 6.3 µg/mL quercetin glycosides in the finished formulation. Three Carrier Variants for Different Water Phases All three variants are water-based and differ in the standardisation or carrier medium. Regardless of the variant, the extract content is approximately 30 percent in each case: Glycerin variant (INCI: Glycerin, Harungana Madagascariensis Extract): approx. 70 percent glycerin, approx. 30 percent extract fraction. Propylene Glycol variant (INCI: Aqua, Propylene Glycol, Harungana Madagascariensis Extract): water approx. 40 percent, extract approx. 30 percent, Propylene Glycol approx. 30 percent. Pentylene Glycol variant (INCI: Aqua, Pentylene Glycol, Harungana Madagascariensis Extract): water approx. 50 percent, extract approx. 30 percent, Pentylene Glycol approx. 20 percent. The recommended use concentration for all variants is 2 to 5 percent; the CDS claim range is stated as 1 to 3 percent. The extract is suitable for vegan formulations and free from fragrance allergens subject to declaration requirements under Annex III of Regulation (EC) No 1223/2009. Further glycerin-based raw materials can be found in our collection of glycerin extracts. Use in Novel Food and Functional Food For food applications, the extract is to be classified as a novel food in accordance with Regulation (EU) 2015/2283; authorisation is required. The CDS cites for this area a function as a nutritive antioxidant as well as references to metabolic health and the reduction of oxidative stress. The recommended concentration in functional food and beverages is 0.5 to 2 percent; at 1.3 percent this results in a calculated 0.93 to 3.9 µg/mL in the formulation. Regulatory relevant here are Regulation (EC) No 1924/2006 for food and Regulation (EC) No 1223/2009 for cosmetics. Safety, Stability and Documentation According to the safety data sheet, the extract is not a hazardous substance under Regulation (EC) No 1272/2008, exhibits no PBT/vPvB properties and contains no endocrine disruptors at or above 0.1 percent. It is not a UN dangerous good and is assigned to storage class 12 (non-flammable liquids). Shelf life is 24 months when stored dry between 10 and 30 degrees Celsius in the original sealed container. Temperature- and storage-related colour changes as well as possible turbidity or precipitates have no effect on quality; filtration can be carried out if required. Full specifications are available in the technical documentation (TDS/SDS/CDS); for information on our gentle production process, please refer to our AVE technology. Sourcing and Consultation for Formulators The dragon blood tree extract complements our range of classic plant extracts as a water-based, antioxidant-oriented raw material with a defined quercetin glycoside marker. For project-specific questions regarding variant selection, specification and regulatory classification, our technical team is available for individual consultation. View Dragon Blood Tree Extract in the CONIUNCTA® shop. CONIUNCTA® - Raw materials, data and services for future-ready formulations.