Angelica Archangelica

Angelica Root Extract (Angelica Archangelica Root Extract): Chlorogenic Acid from the Root in Three Carrier Variants

Angelikawurzel Extrakt (Angelica Archangelica Root Extract): Chlorogensäure aus der Wurzel in drei Trägervarianten - CONIUNCTA

Angelica Root Extract (INCI: Angelica Archangelica Root Extract) is obtained from the root of Angelica archangelica. CONIUNCTA® offers it in three water-based carrier variants: with Glycerin, with Propylene Glycol, and with Pentylene Glycol. The product is of conventional quality and is intended primarily for the food industry. Relevant for formulators are the clearly defined lead marker and the regulatory framework derived from the furocoumarin content.

Chlorogenic Acid as Analytical Lead Marker

Chlorogenic acid is listed as the primary marker of the extract in the CDS. The indicative content in the product is 49 to 252 µg/mL; the literature content of the drug is stated as 0.2 to 0.8 % (ESCOP Monographs, 2nd). This defined marker enables analytical characterisation of batches and forms the basis for quality assurance. Regardless of the respective carrier variant, the extract content is approximately 30 %.

Imperatorin and the Furocoumarin Context

Imperatorin is also listed in the CDS as an active constituent, a furocoumarin for which no concentration data are provided. Due to the furocoumarin content, the extract is phototoxically relevant: the CDS explicitly refers to the required phototoxicity assessment in accordance with SCCS/1557/15. This regulatory note must be taken into account by the formulator in every application assessment.

Primarily a Raw Material for the Food Industry

This product is intended primarily for the food industry. Cosmetic use is only possible with restrictions, as the extract contains furocoumarins and is phototoxically relevant (see SCCS). For food suitability, the Glycerin variant is designated in the metafield. The suitability of the raw material for the respective application, use, and process must be assessed independently by the customer.

Carrier Variants and Composition

The three variants differ in their standardisation and carrier system:

  • Glycerin variant: INCI Glycerin, Angelica Archangelica Root Extract; Glycerin (≥ 99.5 %, anhydrous) approx. 70 %; extraction solvent purified water (not remaining in the final product).
  • Propylene Glycol variant: INCI Aqua, Propylene Glycol, Angelica Archangelica Root Extract; standardisation medium Propylene Glycol/water mixture.
  • Pentylene Glycol variant: INCI Aqua, Pentylene Glycol, Angelica Archangelica Root Extract; standardisation medium Pentylene Glycol/water.

All variants are clear liquids with a characteristic colour (amber to light brown), with a relative density of 1.03 to 1.06. The plant part used is the root of Angelica archangelica, of vegetable origin. As a reference: 1 kg of CONIUNCTA® extract contains the hydrophilic and lipophilic constituents of approx. 35 g of dried or approx. 220 g of fresh drug. Further water-based systems can be found in our overview of glycerin extracts.

Handling, Storage, and Stability

According to the SDS, the product is not a hazardous substance under Regulation (EC) No. 1272/2008 and is not a UN transport hazardous material. During processing, vapours and aerosols must not be inhaled; eye protection is required, skin protection is not. Storage should be dry, in the original sealed container; the stated shelf life is 24 months. Colour changes during the storage period as well as possible turbidity or precipitates may occur and have no effect on quality; filtration may be required if necessary.

Documentation and Ordering

For Angelica Root Extract, we provide the technical documents (TDS, SDS, CDS) as well as batch-specific certificates of analysis (CoA) via our technical documentation. Background information on our manufacturing process can be found on the page about AVE technology. You can review the three carrier variants of the product directly here: View Angelica Root Extract in the CONIUNCTA® shop. Our technical team is happy to advise on the individual assessment of the field of application and regulatory framework.

CONIUNCTA® – Raw materials, data, and services for future-proof formulations.

Tags: Angelica Archangelica Angelica Archangelica Root Extract Chlorogenic acid Furanocoumarins Imperatorin

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