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Nettle Extract (Urtica Dioica (Nettle) Extract): Chlorogenic Acid as Marker for Antioxidative and Conditioning Formulations
The CONIUNCTA® Nettle Extract (INCI: Urtica Dioica (Nettle) Extract) is a botanical liquid extract from Urtica dioica. Chlorogenic acid serves as the lead marker with an indicative range of 122 to 630 µg/mL in the product. The extract is available in three carrier variants (Glycerin, Propylene Glycol and Pentylene Glycol), making it compatible with a variety of cosmetic and food-grade formulation environments. For formulators, the product is a versatile botanical building block with a documented antioxidative profile. This is a product of conventional quality. Chlorogenic Acid as Analytical Lead Marker The characterisation centres on chlorogenic acid, whose indicative content in the product ranges from 122 to 630 µg/mL. At a use concentration of 2 %, the extract delivers a calculated 2.4 to 12.6 µg/mL chlorogenic acid in the finished formulation; at a food application level of 1.3 %, this corresponds to 1.5 to 7.9 µg/mL. These figures enable a traceable link between the amount used and the marker content in the final product. In addition to the primary marker, the CDS documents further confirmed compounds: Scopoletin at 0.02 to 0.08 % (relative to the dry plant) and beta-Sitosterol at 0.1 to 0.5 % (in the root). These accompanying substances complete the compositional profile of the extract. Documented Activity Profile The CDS lists several documented effects and regulatory claims for the Nettle Extract. These include antioxidative properties (ROS scavenging), UV-absorbing activity in the range of 290 to 320 nm, and an anti-aging approach targeting MMP-1 inhibition. The properties balancing, moisture-promoting, conditioning and skin-plumping are also documented. As cosmetic targets, the data sheet specifies ROS scavenging, MMP-1 and UV absorption. For formulators, this provides starting points for antioxidatively oriented skin care and hair care concepts. We intentionally present these statements in close alignment with the data sheet and without any medical interpretation. Three Carrier Variants for Different Systems The extract is available in three carrier systems, each described by its own technical data sheet: Glycerin variant (INCI: Glycerin, Urtica Dioica (Nettle) Extract): Glycerin accounts for approx. 70 % of the finished product, the extract fraction for approx. 30 %; the extraction solvent is purified water, which does not remain in the final product. Propylene Glycol variant (INCI: Aqua, Propylene Glycol, Urtica Dioica (Nettle) Extract): Composition of approx. 40 % water, 30 % extract and 30 % Propylene Glycol; CAS No. 84012-40-8. Pentylene Glycol variant (INCI: Aqua, Pentylene Glycol, Urtica Dioica (Nettle) Extract): Pentylene Glycol/water mixture as the standardisation medium; extraction likewise via purified water. Regardless of the variant, the extract content is approx. 30 %. The choice of carrier variant can be made according to the specific requirements of your formulation. An overview of further water-soluble systems can be found in our category of glycerin extracts. Use Concentration and Fields of Application The product data sheet states a general use concentration of 2 to 5 %. The CDS differentiates this by application: 1 to 3 % is recommended for cosmetics, and 0.5 to 2 % for functional food and beverages. In the food sector, the extract targets metabolic health and reduction of oxidative stress according to the data sheet. The glycerin variant is intended for food applications; all variants are suitable for cosmetic applications. We do not provide specific formulation recommendations; our technical team is available for individual consultation. Specification, Storage and Safety The extract is a clear, light-green liquid with a characteristic colour and a density of 1.03 to 1.06. The shelf life is 24 months when stored dry between 10 and 30 °C in the original sealed container. Colour changes may occur during storage depending on temperature; in the event of turbidity or precipitation, filtration is possible without affecting product quality. According to the SDS summary, the product is not a hazardous substance within the meaning of Regulation (EC) No. 1272/2008, is not a UN dangerous good, and has no PBT/vPvB properties. It complies with REACH Regulation (EC) No. 1907/2006. The complete technical documentation is available via our technical documentation page; individual values such as pH and refractive index can be found in the respective CoA. Request Nettle Extract for Your Formulation The CONIUNCTA® Nettle Extract is produced using our AVE technology and forms part of our selection of classic plant extracts. For samples, specifications and expert advice on the three carrier variants, please contact us: View Nettle Extract in the CONIUNCTA® shop. CONIUNCTA® - Raw materials, data and services for future-proof formulations.
Devil's Claw Extract (Harpagophytum Procumbens Root Extract): Harpagoside as a Lead Marker for Antioxidant Formulations
Devil's Claw Extract (INCI: Harpagophytum Procumbens Root Extract) is obtained from the root of Harpagophytum procumbens and is available to formulators in three carrier variants: Glycerin, Propylene Glycol and Pentylene Glycol. The extract content is approximately 30% across all variants. As a plant-based, vegan raw material, the extract is suitable for cosmetic applications under EC No. 1223/2009 as well as, in the Glycerin variant, for functional food applications. This article summarises the markers documented in the data sheet, the efficacy profile and the technical parameters for formulation development. Harpagoside: the characteristic iridoid glycoside lead marker The lead marker of the extract is harpagoside, an iridoid glycoside. The product specifies an indicative content of 122 to 945 µg/mL. At a use concentration of 2%, this results in a calculated 2.4 to 18.9 µg/mL harpagoside in the finished formulation. For food and beverage applications, a dosage of 1.3% yields 1.5 to 11.8 µg/mL accordingly. In addition to harpagoside, further characteristic compounds of the drug have been identified: procumbide (0.1 to 0.3%) and harpagide (0.5 to 1%). These markers allow analytical characterisation of the root extract and support specification testing during incoming goods inspection. Documented efficacy profile and molecular targets The CDS lists antioxidant, anti-inflammatory and capillary-strengthening properties for Devil's Claw Extract. The cosmetic claims documented are "Balancing", "Elasticity support" and "Anti-inflammatory". At the molecular level, the targets identified are ROS scavenging, MMP inhibition and NF-κB. These statements refer to the cosmetic and food technology application spectrum of the raw material. They are not to be understood as medical or disease-related claims. The final evaluation of claims for a specific end product is the responsibility of the responsible person in accordance with the applicable regulatory requirements. Three carrier variants for different formulations The choice of carrier determines the field of application: Glycerin variant (INCI: Glycerin, Harpagophytum Procumbens Root Extract): anhydrous glycerin (≥ 99.5%) accounts for approximately 70% of the final product; purified water serves as the extraction solvent and does not remain in the final product. This variant is also suitable for food and functional food applications. Propylene Glycol variant (INCI: Aqua, Propylene Glycol, Harpagophytum Procumbens Root Extract): aqueous propylene glycol/water mixture. Pentylene Glycol variant (INCI: Aqua, Pentylene Glycol, Harpagophytum Procumbens Root Extract): indicative values approx. 50% water, approx. 30% extract, approx. 20% Pentylene Glycol. All variants are specified as clear liquids with a characteristic colour (amber to light brown) and are suitable for cosmetic applications. An overview of further water-based extracts can be found in our category Glycerin Extracts as well as in the classic plant extracts. Use concentration and physical parameters The recommended use concentration in cosmetics is 2 to 5% (specified in the CDS as 1 to 3% as an efficacy-related range). For food and functional food applications, 0.5 to 2% is indicated. The relative density is between 1.03 and 1.06. Specific individual values for pH, density and refractive index should be taken from the product-specific CoA. Note on storage stability: depending on temperature, colour changes may occur during the storage period; in the event of turbidity or precipitation, filtration is possible without impairing product quality. The shelf life is 24 months when stored dry between 10 and 30 °C in the original sealed container. Safety and documentation According to the SDS, Devil's Claw Extract is not a hazardous substance within the meaning of Regulation (EC) No. 1272/2008. No hazard pictograms, signal word or H/P statements are assigned; PBT/vPvB and endocrine-disrupting properties (≥ 0.1%) are not present. The raw material is not classified as dangerous goods under ADR/RID, IMDG and IATA. Complete TDS, SDS and CDS as well as batch-specific certificates of analysis are provided to registered customers via the technical documentation section. Purchasing and technical advice Devil's Claw Extract is available as a vegan, plant-based raw material for cosmetic and food applications in all three carrier variants. Our technical team is happy to provide individual advice on selecting the right variant and adapting it to your formulation. View Devil's Claw Extract in the CONIUNCTA® shop or discover the full range in the product list. CONIUNCTA® - Raw materials, data and services for future-proof formulations.
Grape Leaf Extract (Vitis Vinifera (Grape) Leaf Extract): OPC for Astringent and Skin-Tightening Formulations
Grape Leaf Extract (INCI: Vitis Vinifera (Grape) Leaf Extract) is obtained from the leaf of the grapevine and delivers oligomeric proanthocyanidins (OPC) as a key marker that is equally relevant for formulators in cosmetics and functional foods. CONIUNCTA® offers the extract in three carrier variants: Glycerin, Propylene Glycol, and Pentylene Glycol. This allows the profile to be flexibly adapted to different systems. It is a conventional raw material in liquid form with a characteristic color ranging from amber to light brown. OPC as the Key Marker of Grape Leaf The characteristic marker of this extract is OPC (oligomeric proanthocyanidins), which belong to the class of condensed tannins. According to the CDS, the OPC content in the product is indicatively 0.7 to 2.5 mg/mL; in dried plant material, the literature reports 3 to 8% (Shi et al. 2003). At a use level of 2%, the calculated OPC content in the formulation is 14.0 to 50.0 µg/mL. In addition to OPC, further compounds have been identified in the extract: Resveratrol (0.01 to 0.1%) as well as anthocyanins (in the skin, 0.5 to 2%). These compound groups define the antioxidant profile of the raw material. Documented Efficacy Profile for Skin Care The CDS lists the following properties for Grape Leaf Extract: astringent, antioxidant protection, balancing, circulation-promoting, moisturizing, conditioning, and skin-tightening (skin-plumping). Mechanistically, protein precipitation and MMP-1 inhibition are described. For cosmetic application, the data sheet lists protein precipitation, MMP-1 inhibition, and pore refinement as targets. This makes the extract a functional building block in formulations aiming for an astringent-conditioning and antioxidant profile. Three Carrier Variants Compared CONIUNCTA® provides Grape Leaf Extract in three water-based systems that differ in their standardization medium: Glycerin Variant (INCI: Glycerin, Vitis Vinifera (Grape) Leaf Extract): The carrier is anhydrous Glycerin (≥ 99.5%) at approximately 70% of the finished product. According to the specification, this variant is also suitable for food applications. Propylene Glycol Variant (INCI: Aqua, Propylene Glycol, Vitis Vinifera (Grape) Leaf Extract): Propylene Glycol/water mixture as the standardization medium. Pentylene Glycol Variant (INCI: Aqua, Pentylene Glycol, Vitis Vinifera (Grape) Leaf Extract): Pentylene Glycol/water mixture as the standardization medium. All variants are clear liquids with a characteristic color; purified water serves as the extraction solvent in each case. All variants are suitable for cosmetic application; the Glycerin variant is intended for food use. An overview of further water-soluble raw materials can be found in the collection of Glycerin Extracts. Use Concentration and Food Application For cosmetics, the CDS recommends a use level of 1 to 3%; the general data sheet specification is 2 to 5%. For functional foods and beverages, 0.5 to 2% is indicated; at a use level of 1.3%, the resulting OPC content is 8.7 to 31.3 µg/mL. The data sheet describes metabolic health and the reduction of oxidative stress as targets in the food sector. We develop specific formulation and dosage recommendations on a product-by-product basis: our technical team provides individual consultation. Processing, Stability, and Storage The shelf life is 24 months when stored dry between 10 and 30 °C in the original sealed container. Color changes may occur during storage depending on temperature; in the event of turbidity or precipitates, filtration is possible without affecting quality. According to the SDS, the raw material is not a hazardous substance under Regulation (EC) No. 1272/2008 and is not classified as dangerous goods. The complete TDS, SDS, and CDS are available via our technical documentation. Background information on our manufacturing process is explained on the AVE Technology page. Sourcing and Further Plant Extracts Grape Leaf Extract complements the broad portfolio of classic plant extracts from CONIUNCTA®. For samples, specifications, and project-related inquiries, formulators and buyers are welcome to get in touch directly. View Grape Leaf Extract in the CONIUNCTA® Shop. CONIUNCTA® - Raw materials, data, and services for future-ready formulations.
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CONIUNCTA® Extraction process
From the plant to the high-purity active ingredient: controlled, gentle, precise.
Entry and disruption of the plant material
Selected plant raw materials are gently processed and their cell structures are broken down in a targeted manner.
Extraction
The released ingredients are concentrated using an optimized extraction process.
Heat treatment and solid-liquid separation
Controlled heat treatment and multi-stage ultra-fine solid-liquid separation stabilize and purify the extract.
End product
The result is a stable, high-purity CONIUNCTA® extract of defined quality.
